DPCstruct | MC28928

Metacluster Properties and Pfam Annotations

Number of structural domains50
Mean domain length (aa)141 ± 20 aa
Standard deviation of domain lengths20.34
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score89.79
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)33.84
Pfam Score100.00
Assigned Pfam label(s) CL0635

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A524PAS9 3-134 GRVKGFRFAGVHSGVKAGDALDLGLVLADEPAAATGVFTKNRVRAAPVVISERRLQSGLAQAIMVNSGNANACTGKQGRLAALALTR…
A0A7C8E8X5 1-133 MTPVPAEAAKNTKNVTVSRGPFEVAGFLAGAVESGMRYSGRLDLALICAQDPAGCAASGVFTRNFFCAAPVELCRERLEKHRARAIL…
A0A356KU95 1-133 None
A0A855HWY5 2-146 None
A0A366SBH0 420-555 None
I7LRE0 1-114 None
A0A3C1WIL8 8-130 None
A0A358GXA9 2-142 None
A0A6N6Q2L3 18-153 None
A0A6I7QN14 21-153 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.