DPCstruct | MC28917

Metacluster Properties and Pfam Annotations

Number of structural domains1056
Mean domain length (aa)135 ± 27 aa
Standard deviation of domain lengths27.48
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score86.68
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)17.63
Pfam Score98.36
Assigned Pfam label(s) CL0023- CL0063- CL0268- CL0109- PF03477

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A661AN74 2-75 AHAPYSGYRVGACLITQDGKEYFGFNIENASYSLTICAERVAFVHALLNGERNFKRIYVTDFPCGACLQFMAEF
A0A2W4T408 4-144 WEARFFQLCALVASWSDDRSRQVGAVIVDTENNVLSIGYNGFPRRVDSVRSHRHSREGGEKYLWIEHAERNAIYSAVRSGASTRGAR…
A0A2K6U5H2 7-140 None
A0A7T8XQM2 7-142 None
A0A1I8IPT0 21-181 None
A0A0K0E2M9 153-281 None
A0A377CC48 42-135 None
R7CJ22 62-195 None
A0A835H5D3 162-323 None
A0A7S1UQ75 9-128 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.