DPCstruct | MC28783

Metacluster Properties and Pfam Annotations

Number of structural domains396
Mean domain length (aa)138 ± 29 aa
Standard deviation of domain lengths28.59
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score89.82
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)15.55
Pfam Score62.08
Assigned Pfam label(s) CL0059- PF21307- PF17137- CL0749- CL0088

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R5IYP9 183-324 IKDYWGGMLREGATSFWEKYNPEETGTQHLAMYGRPYGKSLCHAWGASPIYLLGKYYLGVTPEEAGYREFRIAPNLGGLKWMEGSVP…
A0A854C564 19-153 IESPLTTLWEGWGIGSEGFGGGTYNHAWSGGPLTILSQYIAGIETLEPAFRMFRVAPHPAHLNFIRTLVPLSGGRRIVFEMDKSAHG…
A0A1V5Z6L0 320-454 None
A0A7V3AF73 124-264 None
A0A370IIF7 5-115 None
A0A396QHN3 163-296 None
A0A4S9JGL3 54-207 None
A0A355IX67 2-117 None
A0A370PBT8 230-389 None
A0A518AMG0 641-812 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.