DPCstruct | MC2878

Metacluster Properties and Pfam Annotations

Number of structural domains58
Mean domain length (aa)163 ± 17 aa
Standard deviation of domain lengths17.49
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score74.70
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)26.92
Pfam Score91.00
Assigned Pfam label(s) CL0010- PF17208- PF12140

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A485MLA2 1-180 MTPLALSPPRSTPEPDLSSIPQDAATIPSLAAPQALTVCLYINKQANAGPYLERRKVQQLPEHFGPERPSAVLQQAVQACIDCAHQQ…
A0A060Z7K2 12-144 QWEILIYVNHRCFSGPYLNKGRIAELPQAVGPGKCTLVLKEVLSMLINAAYKPGRVLRELQDVEDQHWDCHEETLKAKYKGKTYRSS…
A0A2A6C8J6 493-631 None
A0A6L5CEG5 239-407 None
A0A4W3HJP6 60-227 None
A0A0B1PKP5 192-354 None
A0A7J5Y802 54-223 None
A0A5C6MFG2 3-138 None
A0A4Y2AT29 199-376 None
A0A1Y3EIB0 322-477 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.