DPCstruct | MC28779

Metacluster Properties and Pfam Annotations

Number of structural domains37
Mean domain length (aa)165 ± 25 aa
Standard deviation of domain lengths24.99
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score78.20
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)39.50
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2R6QES6 16-161 LASASYNDERGPPPHPFWRRSNVPPQGYFDPKDNGGSLLTQVPGTFPAGLGEPLNVIMSANSDSDVLKDQETDGGLRNYFLSLGYSS…
A0A166EDS0 1-156 MSRRSNVPSDGFYVPAANGGSQLTIVEDTFPAGLGEPINVIISAKSDSAVLKDQPNDGGLRNYFQSIGFSGECLGQHEGDDQQADLG…
A0A146ICU5 786-968 None
A0A4T0HV42 41-172 None
A0A4U0W6V3 402-578 None
J8TJD9 1-168 None
L0I7Q1 23-221 None
A0A0C3BWD2 2-142 None
A0A146I6Q5 3-153 None
A0A166I997 1-163 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.