DPCstruct | MC28759

Metacluster Properties and Pfam Annotations

Number of structural domains143
Mean domain length (aa)172 ± 25 aa
Standard deviation of domain lengths24.65
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score85.23
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)22.97
Pfam Score90.00
Assigned Pfam label(s) CL0331- CL0037

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A8IF62 231-378 NDPVTKDLDPTKKALLNAIAGGESGGRYNLRWSPKGTALFNDFSKHPRIFEPGPEGPSSAAGRYQITATTWDRIMGPNTPFTPENQD…
A0A0J6BCN4 20-179 PEAAQGNARYALSDQRRALLETIRYAEGTWRNGSSDGYRTLYGGSLFQGLARHPEITVRRRYTSAAAGAYQFLPGTWREVAGQLRLR…
A0A3D1PHP1 5-163 None
A0A809RLF6 413-561 None
A0A0M5KL94 155-297 None
A0A522XMH6 187-375 None
A0A7Y5D8U0 315-500 None
A0A0S9REZ8 2-131 None
A0A2G9WPI4 289-423 None
A0A3P3DJL6 84-267 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.