DPCstruct | MC2874

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)80 ± 6 aa
Standard deviation of domain lengths6.40
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score88.55
Mean fraction of residues predicted as intrinsically disordered0.80
Mean length-normalized TM-Score0.91
Mean intra-cluster local Distance Difference Test score0.92
Mean intra-cluster sequence similarity (%)46.56
Pfam Score100.00
Assigned Pfam label(s) CL0719

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H6N249 42-120 ILNDRNEEKRITEAEKNERVQRQLKTLTDELAQARDEDMKTQNDLIHRENMRQGRDKYKTLRQIRQGNTKQRIDEFEAM
A0A183Q000 38-116 AVNNVDEDLRQSKQDTDEDHATRLKLLRQDLSSVRNPNKMQAIDIHYEDIVSKGMDKYRTLRAIREGNTKKRVDQFESM
E4YGL7 229-298 None
A0A0N4T0I9 209-281 None
A0A1I8HTK0 212-286 None
A0A7R8H6W0 187-275 None
A0A5J4NFI6 285-358 None
A0A4Z2G2K6 295-378 None
A0A6F9C2Z0 290-367 None
A0A3R7ST05 111-197 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.