DPCstruct | MC28729

Metacluster Properties and Pfam Annotations

Number of structural domains44
Mean domain length (aa)188 ± 35 aa
Standard deviation of domain lengths34.55
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score89.42
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)38.36
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
B0E8F1 28-188 LSEPYGKNFDNEFKPYYSPKQMLKMGVFEGKYLNDCVNEFPIEWYDESKDKRSLVADPKLNYFGVKSRQSLTTWKKNGWIPVCKGDY…
A0A553PTI0 20-224 VKQGVSTTAQADRTAPPPQRNARGQLEFEGFPMFRPNRTPAQVLQAGSFGGTYFRPIYSSVTGEKYGASVWQELPDHWLTGLNVKTQ…
A0A7K3ZHC4 117-282 None
A0A7S0ITN7 3-127 None
A0A4Q4XP86 9-210 None
A0A7S3BA87 194-345 None
A0A7S0DLI0 10-182 None
A0A813F737 22-235 None
A0A2P6NIS9 157-368 None
A0A645C663 2-126 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.