DPCstruct | MC28675

Metacluster Properties and Pfam Annotations

Number of structural domains317
Mean domain length (aa)141 ± 27 aa
Standard deviation of domain lengths26.84
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score86.25
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)19.56
Pfam Score96.07
Assigned Pfam label(s) CL0305- CL0031- PF00590- PF21234- CL0172

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U9JBV1 2-99 VCLGNICRSPLAHGIMEFMVKENGLDWEIDSAGTGDWHVGHAPDKRSVQVAKDRGIDISGQRAQLFDPAFFSSYDRILVMDRQNYND…
A0A413DE17 15-168 KGKHTVLFICLGNICRSPAAEGIMKSLVEKAGLQDEFEIDSAGIGGWHVGQLPDSRMRKCGAEHGYNFNSHARQFQKSDFARFETIV…
A0A2R6CYM3 2-118 None
A0A1B0C2K5 71-185 None
A0A354SBF7 4-169 None
D6T0J2 5-133 None
A0A2V9TFL1 229-382 None
A0A6J7UUF1 2-128 None
A0A3D1F993 2-93 None
A0A259ME25 36-142 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.