DPCstruct | MC28661

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)131 ± 9 aa
Standard deviation of domain lengths9.42
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score83.40
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)32.48
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A444ULF4 147-278 MIGRELFSRFPALYPFLLRQLETVASTVDGDSGVLKLHPCLFLLLLILGRLYPSPMDGTSSTLSLAPFVPFIIRCGRSPVWRSREMA…
H3DEK2 120-252 MSPPAFFHHYPGLQPFLLAELSGAAQELQDPSNEAKLHLQPSLFPVLTLLAQLQPGVQDATATLSSFLPPLLQLSSSPIYNVRVMAS…
A0A835GFD0 1-128 None
F6YB51 132-253 None
Q553Q9 1409-1564 None
E2B2U2 465-594 None
A0A6P4E0Q0 1-119 None
A0A7F8RM29 1-135 None
A0A2R7X1Y4 27-148 None
A0A811WUQ5 381-507 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.