DPCstruct | MC28587

Metacluster Properties and Pfam Annotations

Number of structural domains2626
Mean domain length (aa)87 ± 15 aa
Standard deviation of domain lengths14.93
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score80.39
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)21.93
Pfam Score97.30
Assigned Pfam label(s) PF03105- CL0020- PF14484- CL0263- PF10240

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H3EHW6 2-81 None
A0A6A2XG74 59-152 None
A0A4U5MLL6 125-211 None
A0A4U5LZZ8 280-363 None
A0A812PBM1 7-82 None
A0A0N4Z208 2-80 None
A0A6P3D7K3 6-100 None
A0A446UFL5 222-296 None
A0A0F7SJC1 779-874 None
A0A2P6NK27 925-1015 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.