DPCstruct | MC28587

Metacluster Properties and Pfam Annotations

Number of structural domains2626
Mean domain length (aa)87 ± 15 aa
Standard deviation of domain lengths14.93
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score80.39
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)21.93
Pfam Score97.30
Assigned Pfam label(s) PF03105- CL0020- PF14484- CL0263- PF10240

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3Q0FPZ7 22-135 None
K0SQ83 34-132 None
A0A5D2XTW9 9-119 None
A0A395NDB8 701-804 None
A0A7H9HVS6 19-105 None
A0A835JYF2 76-188 None
A0A0L0C4B9 5-103 None
H2LRQ4 343-437 None
A0A2S2NV50 139-244 None
F1A2K0 316-426 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.