DPCstruct | MC28587

Metacluster Properties and Pfam Annotations

Number of structural domains2626
Mean domain length (aa)87 ± 15 aa
Standard deviation of domain lengths14.93
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score80.39
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)21.93
Pfam Score97.30
Assigned Pfam label(s) PF03105- CL0020- PF14484- CL0263- PF10240

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E0W373 387-462 None
A0A1W4WI59 194-286 None
A0A669PQN9 11-75 None
A0A5B6WSA5 25-138 None
A0A401QAT0 2-74 None
A0A0E0D2A2 255-330 None
A0A1Y2FNB4 269-359 None
A0A0F9YNW5 187-251 None
A0A0F9ZA15 22-90 None
A0A3B3ZX75 2-66 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.