DPCstruct | MC2858

Metacluster Properties and Pfam Annotations

Number of structural domains160
Mean domain length (aa)258 ± 40 aa
Standard deviation of domain lengths40.47
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score82.67
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.37
Mean intra-cluster sequence similarity (%)10.12
Pfam Score29.98
Assigned Pfam label(s) PF04381- CL0063- PF13092- PF15969- PF19614

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D7XY29 30-366 RPIIASLGLPTGRGREATNEKILESLIDLKSKDRQKFDGIMANVNDLILGQVVYGEKAIFSLTVDNSVIKTLNDRFSFQWNLMNQPS…
E7QYB4 15-272 VKDTYSGKIFQLASTSEELNFDLLKEHLTNRTIHLDPPDDYLDKEDLEVPRVFTDESGDIKIVTTIEEVRHVETSEFEALTGSIVLD…
A0A1Q9SLE2 16-274 None
A0A6M1YHG9 7-304 None
A0A3M1CVN9 83-403 None
A0A5C5YEE0 129-465 None
A0A177ULJ5 362-665 None
A0A6A9SCZ1 3-217 None
A0A7U8V9Y2 2-211 None
A0A1Y6FAI5 7-238 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.