DPCstruct | MC2852

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)190 ± 18 aa
Standard deviation of domain lengths17.59
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score84.13
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)19.75
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4V3CBP8 2-162 TTLTFPIGHCLGTVHAAGSHVQQVRLGGEIVDLADEEFAVWALAHALTGGRGPLIDSLLARNLLVEVDVNNPAGFAERHRLLPLNLG…
A0A1R4F4Y2 231-434 PADPTRVPELHRIGWDLGFALVDGGSVWRIVDRGHVIIEMSREEYVVWTSAAGRPATVDGSWTLADANERAQSLAVPRPEPILRALL…
A0A0F0GJD1 2-153 None
A0A2W1TN39 8-209 None
A0A8A5YT29 224-408 None
A0A846B0A2 8-194 None
A0A2S6IP07 23-222 None
A0A2T0ZZT6 10-212 None
A0A2G6XDW3 295-501 None
A0A2W6C882 1-203 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.