DPCstruct | MC28484

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)202 ± 23 aa
Standard deviation of domain lengths23.06
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score81.53
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)30.47
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2E9CMI3 9-204 SAEGRPILMCQLVRPTGSTRIDRASLAHSHWACIDAQTFKAFWDEEVAAAEGRLDLETIWVATGLLLPVWNRLPQDDVRVWRIDNGA…
A0A7X7IRX7 1-160 WWNAEYEKTPAREPQRFHILSGAIFPIYDKVMGSSGIRNVKIARAILVDGQALVGLNLSPADVPNVKQRLGIGTPLATASPAAILEL…
A0A4D8QAC5 455-661 None
A0A1X7MSY7 1-266 None
A0A4R2SCD5 749-952 None
A0A2N3AXK9 2-197 None
A0A7X4ENQ5 156-356 None
A0A7Z8FVV2 74-278 None
A0A4P7ZDX0 253-454 None
A0A6P1BB88 31-186 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.