DPCstruct | MC28479

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)120 ± 10 aa
Standard deviation of domain lengths10.35
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score76.85
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)47.87
Pfam Score100.00
Assigned Pfam label(s) CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A812T3C6 170-289 GEGAQGGEGTQGPEDGDQVMADSVQKVEEVIESNGSLFFSSIPKQMRKGRGETAEETTKLHMDRTLQLEQMLAREYSGNELAMLGEL…
A0A453A8K2 1-116 MDRAPQTDMERRLMEQLREDKFAKKAPAQPERRGCYYTTIPASVKHRNISADELTLLNLDRTSLLETVLAKSYQGQEDLLLGELQFS…
A0A444GEM3 235-356 None
A0A1R2BPQ6 137-234 None
A0A1Y1IGB0 386-500 None
A0A835VNJ7 488-623 None
M8AJT0 447-572 None
A0A1D6EFH8 1-126 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.