DPCstruct | MC28450

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)190 ± 23 aa
Standard deviation of domain lengths23.48
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score85.42
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)22.99
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4V3SX95 22-227 VASDPVQDHQDATTALEKAICQELNHPPLGAFTEVPDRRGTVIEKWTRRLAKAEPTPLHALLVMDGSPVDARFVDPLTGMPVLRSPD…
A0A0J8U9R0 151-329 IGCTIRSGPGRGPLAQEWVTRLKPIGSDPESLGSMFAEAKLTTEQLGSAQWSWWEDYENPDCWAIRSADDVVDATVGTRIPGIDGRW…
H2KAD7 1-197 None
A0A7X0K6G4 133-302 None
A0A1Q4VJ69 15-149 None
A0A1V2Q4D7 93-286 None
A0A399GHD9 1-240 None
A0A1S1NI81 318-513 None
A0A1I2CH00 917-1113 None
A0A0M9YEK2 243-421 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.