DPCstruct | MC28435

Metacluster Properties and Pfam Annotations

Number of structural domains1981
Mean domain length (aa)154 ± 29 aa
Standard deviation of domain lengths28.99
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score84.74
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)15.29
Pfam Score98.75
Assigned Pfam label(s) CL0213- CL0125- PF03140- CL0027- PF07589

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1F5QBE0 4-132 None
A0A158QW68 2-135 None
A0A0R3UNM0 1-136 None
A0A0R3U6F1 7-124 None
A0A0R3U5K2 2-121 None
A0A0R3U2S4 2-120 None
R6GSQ5 72-220 None
A0A2C9VGY5 3-162 None
A0A4Z0J7X0 145-353 None
A0A4Y9T3W4 11-143 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.