DPCstruct | MC28368

Metacluster Properties and Pfam Annotations

Number of structural domains72
Mean domain length (aa)128 ± 17 aa
Standard deviation of domain lengths16.60
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score75.60
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)20.27
Pfam Score100.00
Assigned Pfam label(s) PF15998

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1I8AN11 159-276 HNGCNCITKNCGCCAHLLVRKIHLNDNACWNITYISEDIGLKVSFSVNDHIYISREISVRNPPPFCFDVPHLRQFAALCLKLFNVET…
A0A1I8NMX5 2-108 CANVTYIQPKQEINLEMFLNENQSAKYAVSTRNPSPFCIPIMLNIPMSMCVQMSDVGLQGDNMHACMDFMVQLASSGLFEMHFQCMQ…
Q8T0Z4 35-175 None
A0A3Q0IT39 5-135 None
A0A7E5VUB7 126-255 None
D6W7K2 48-178 None
D6W6H0 15-129 None
A0A3L8DPI8 8-125 None
A0A2T7PVS9 55-201 None
A0A2T7P868 195-334 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.