DPCstruct | MC28365

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)218 ± 24 aa
Standard deviation of domain lengths24.28
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score88.34
Mean fraction of residues predicted as intrinsically disordered0.15
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)27.32
Pfam Score66.67
Assigned Pfam label(s) CL0110- PF12529

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183TX70 210-433 GNLHLTNWKRKQGCRCAMLKKVVDWCGCSPLVFNDLDIPKFMLETSKKKVIFFGRKFDSLISQSAIAAAESQALRRTPQLVDANHVS…
A0A1I8AI07 1-176 MVFREPKISSFHLDRAKARTVYFARKFDSMIDVNPIAAAERQSMRNRLHLIQKDHPAFNSTWVNFYSVAGDGDSRRASIYQQLSSLF…
A0A6A4WAG0 28-244 None
A0A2G9RJA2 3-201 None
A0A2H2IE15 2-211 None
A0A1S3QSL7 1-210 None
A0A0A9WGN7 75-292 None
A0A183C899 535-771 None
A0A267EM15 193-468 None
A0A4U5VSV6 451-688 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.