DPCstruct | MC28362

Metacluster Properties and Pfam Annotations

Number of structural domains47
Mean domain length (aa)96 ± 7 aa
Standard deviation of domain lengths6.72
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score91.89
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)45.00
Pfam Score100.00
Assigned Pfam label(s) CL0099

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A022QK52 139-237 PVEKIVENMEGVRCKRVARCISSVGLYVPGGTAVLPSTALMLSVPAQIAGCKTIVLATPPAQDGSICKEVLYCAKKAGVTHILKAGG…
A0A1I8AF09 2-99 QDSWTYTEADGTVLGQKVTPLDRAGLYVPGGKASYPSSVLMNAIPAKVAGVSEVVMVVPTPRGEINELVLAAACIAGVDRVFTIGGA…
A0A094A240 518-623 None
A0A2K1QNJ2 97-194 None
A0A5N5DSL0 888-995 None
A0A316FPE0 106-197 None
H0EXP9 266-361 None
A0A447RKR2 107-210 None
A0A0A0LVH0 747-845 None
A0A0L8VW28 226-330 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.