DPCstruct | MC2835

Metacluster Properties and Pfam Annotations

Number of structural domains39
Mean domain length (aa)180 ± 16 aa
Standard deviation of domain lengths16.43
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score92.49
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)25.44
Pfam Score90.28
Assigned Pfam label(s) PF07364- PF07171

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A836CFF6 420-611 ARVAAGGDTPPILLADISDNPGGGARGNTTWMLRALHEARIPGVVLGLFTDEALAETARQAGVGVRFDAIFNAVESEFARRFETGVT…
A0A2E0E5H8 183-360 ELSQKTTRPVIIADPQDNPGAGASGDSTGLLSQLIQSKVPALVGMFWDPNAANHCHTVGLGKTITIDIGGKFPRENGPALTITGVIK…
A0A4V2D886 81-248 None
A0A1F3SGX6 44-226 None
R8BHQ3 637-816 None
A0A3M1D9S7 447-637 None
A0A4P5SSF6 291-483 None
N9QFN0 164-363 None
A0A7S2CYI1 6-187 None
A0A3D8SX90 525-714 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.