DPCstruct | MC28349

Metacluster Properties and Pfam Annotations

Number of structural domains1601
Mean domain length (aa)142 ± 28 aa
Standard deviation of domain lengths28.03
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score86.40
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)14.22
Pfam Score93.15
Assigned Pfam label(s) CL0063- CL0057- CL0104- CL0123- PF01329

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A839QXI7 46-179 LHMRYDLISAGELVRIDHFNQVTPDVPRGRKYLEELGFRVTEDIKDEAGTTYAAWMHRKGTVHDTALTGGDGPRLHHIAFATHEKHN…
A0A543QWB2 12-155 SSLFADIRGHHIAIRVPDRDVAIKWYQDKLDWRVVYMWAYGDQQLAFLAPPNDDRFMVELLAGGDPSPHPLPPYKDLADSLRYAGYH…
A0A1I2P5N2 2-109 None
A0A2D9Q2J8 41-152 None
A0A1H9F6T2 2-138 None
A0A291QN97 54-249 None
A0A424L3L2 4-146 None
A0A3R7RR85 2-114 None
A0A557R1U3 2-144 None
A0A6J7S7T4 2-121 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.