DPCstruct | MC28312

Metacluster Properties and Pfam Annotations

Number of structural domains72
Mean domain length (aa)247 ± 48 aa
Standard deviation of domain lengths48.02
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score75.70
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)23.57
Pfam Score98.65
Assigned Pfam label(s) CL0292- CL0026

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W0EFK7 9-258 LREGVEISIILAIILAYLKQLGASRASGKVWLGTAAAALVSLLTGVVIFFVLGKTEMGDFQEILEGTFMLVAVVILTWMTLWMKRQS…
X1GWV8 31-214 KTIEKMEQSIERQKAFSISLLTFIIIIREGIELVLLLTGTASIGSINQTTIGIGSIIGIGISVIIGLLTFYGIKSIDLSKFFKATNL…
A0A6N2TE07 449-706 None
L0D920 468-728 None
A0A135V4C3 1-175 None
A0A812PBX1 79-388 None
K0ZHA6 500-747 None
C4LLP3 1-199 None
A0A353FFX2 196-442 None
A0A538TGT8 1-277 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.