DPCstruct | MC2827

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)200 ± 21 aa
Standard deviation of domain lengths21.02
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score85.91
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)22.85
Pfam Score100.00
Assigned Pfam label(s) CL0291

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
X1NXB3 10-201 TARFMLMLSRYKDLNLDFVHKRVKIIDTLDYSLYNTYIELVKASFKGFYDVLDKIAYFINDYLRLGIPDRRVSFRAVWYQSSRDKTI…
A0A181C8S3 14-209 GVTLTNTLDYPLYSLASERVRTAFRIAYSLLDKIAFLIDRYWKLGKIPAHISFKNVWMVEKKQRLLPQFAESNNWSLRGLYWLSKEL…
A0A7H8PP50 1-163 None
A0A8B3R840 4-198 None
A0A7H9DQN8 11-223 None
A0A4Q2Y2W9 47-257 None
R6PPR2 28-206 None
A0A497RLU1 72-296 None
A0A3S0E3E0 264-488 None
A0A5M8GHM7 2-199 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.