DPCstruct | MC2826

Metacluster Properties and Pfam Annotations

Number of structural domains705
Mean domain length (aa)192 ± 32 aa
Standard deviation of domain lengths31.59
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score87.24
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)22.56
Pfam Score96.69
Assigned Pfam label(s) CL0276- CL0161- CL0681- CL0304- CL0237

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1U1C8X0 2-171 None
A0A1U1CPN5 6-205 None
A0A6H1WUR4 16-220 None
A0A1F4K2X4 108-288 None
A0A1V5N7J5 110-309 None
A0A564U8U0 1-155 None
A0A1H3GSD0 116-317 None
A0A661XG34 210-404 None
A0A5P9NGR3 454-681 None
A0A7C4TFB5 7-181 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.