DPCstruct | MC2826

Metacluster Properties and Pfam Annotations

Number of structural domains705
Mean domain length (aa)192 ± 32 aa
Standard deviation of domain lengths31.59
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score87.24
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)22.56
Pfam Score96.69
Assigned Pfam label(s) CL0276- CL0161- CL0681- CL0304- CL0237

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6H9HZ69 356-541 None
A0A444ITW4 4-117 None
A0A2N2DR81 235-404 None
A0A6J4UGU6 445-639 None
A0A7T9DJ35 63-264 None
A0A349LM84 109-263 None
A0A5C4Y8J2 147-312 None
A0A7V9TIH5 141-350 None
A0A373C4M4 5-222 None
A0A7C3W7R0 3-139 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.