DPCstruct | MC2826

Metacluster Properties and Pfam Annotations

Number of structural domains705
Mean domain length (aa)192 ± 32 aa
Standard deviation of domain lengths31.59
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score87.24
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)22.56
Pfam Score96.69
Assigned Pfam label(s) CL0276- CL0161- CL0681- CL0304- CL0237

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A316S665 4-174 IDEMKTLLQEALPPKRFKHSLGVYETALKMAEHYGMEKEKIAIASLLHDCGREVPTDQQVAKAEELGLEVDYVERRQPILLHAKLGA…
A0A2M7NZU6 314-508 IENKRLITVIKTNLINITRSLAEAIEAKDSHTRGHCERTAWYAVATARELNMPKAVIETIEIATLLHDIGKIGIPENILLKPGGLTQ…
A0A2Z3JL60 24-163 None
A0A6J4JMV1 143-354 None
A0A4Q3K1N6 149-317 None
A0A7V9SGP9 159-322 None
A0A6L9ITR0 446-700 None
A0A0S7ZRW7 37-208 None
A0A7X7KUF6 387-642 None
A0A511N404 15-171 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.