DPCstruct | MC2825

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)95 ± 10 aa
Standard deviation of domain lengths9.78
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score90.84
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)27.92
Pfam Score100.00
Assigned Pfam label(s) PF07372

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A379N8U8 1-82 MVLRKGDPDSGGILCVLHGREGMVVLSQVRDAEGRQAWMRGTGATAVNQETADAYVARQVKRDPDLWVLEFEAPDLLPPFEA
A0A3C1BQG5 64-156 VQALVRRVNSECIGVIARRGDTDAGGIYVRVNRLDGRSGLLVAFTDMNGERRWRVLASHLTPDDQIEDMLVREIARDPDMWVVEIED…
A0A2A2KGC2 1-75 None
A0A1E3H8C1 167-267 None
A0A3B0TN26 2-105 None
H6SNS0 194-289 None
X5MMS4 8-96 None
A0A2W5MZ69 23-122 None
A0A845QA83 1-113 None
E0TH79 2-86 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.