DPCstruct | MC2824

Metacluster Properties and Pfam Annotations

Number of structural domains60
Mean domain length (aa)114 ± 10 aa
Standard deviation of domain lengths10.27
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score73.95
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)60.10
Pfam Score100.00
Assigned Pfam label(s) PF12020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
S4R8J5 1-92 HVKMGTCEVVEAHRCCNKNKIEERSQTVKCSCLPGQVAGTTRARPSCVEASIVVQKWWCEMKPCLEGEECKVLPDRGWTCSNGNKVK…
A0A7N4PVX0 276-403 FRSWSTGVCLLVLCLATLWARLAFASSHPRTHAVHVEPGTCEVIAAHRCCNRNRIEERSQTVKCSCFPGQVAGTTRAKPSCVDASIV…
A0A4U5UQ07 137-245 None
A0A835NEU0 12-133 None
A0A3B5Q2Z9 15-137 None
A0A556UG53 322-441 None
G3IDS6 24-124 None
A0A4U5U9K6 43-175 None
A0A3Q2H1Y1 101-222 None
A0A2R8QI81 4-117 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.