DPCstruct | MC2819

Metacluster Properties and Pfam Annotations

Number of structural domains3267
Mean domain length (aa)360 ± 72 aa
Standard deviation of domain lengths72.03
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score89.37
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.34
Mean intra-cluster sequence similarity (%)11.45
Pfam Score82.18
Assigned Pfam label(s) PF18951- PF00057- PF21307- PF11945- PF13968

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5J6SDC9 162-511 LWLGLDGLKMQGTNGSQLWDTAFAVQALLEAGAQNIPAFTDCLNQAHAYFEVTQVRDNPPDYDKYYRQMNKGGFPFSTRDCGWIVTD…
A0A2V9RPT7 32-379 TKERVRAAVEWILRAQDAAGDGGVSMGYFPCENPGAWKTSYPETTGYIISSLLEFARCYRDEKVRQRAIKMAEWEIKVQMRSGAVQG…
A0A446JWE7 119-438 None
A0A7S3ZNW7 199-630 None
A0A258RJ95 102-513 None
A0A819NIU7 149-549 None
A0A7V2UZ23 166-505 None
A0A7V3ADK9 34-365 None
A0A1G0ZRX3 59-490 None
A0A1V2LS39 37-522 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.