DPCstruct | MC28158

Metacluster Properties and Pfam Annotations

Number of structural domains330
Mean domain length (aa)147 ± 31 aa
Standard deviation of domain lengths30.76
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score71.99
Mean fraction of residues predicted as intrinsically disordered0.51
Mean length-normalized TM-Score0.41
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)16.13
Pfam Score89.47
Assigned Pfam label(s) PF10748- CL0655

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1W7QPL7 2-85 LPIQSFEVTKFKVAGIIAGLRENQALVIDPNGKGYVVRAGMAIGNANGRISRITSSSVEVVERYRDGGGRTKSRTIVLTLPKKR
A0A6I0E8W5 28-167 WTAIDAGPIFPAAVPKTLQTDSPGSNQGVEALDASVDSSVVTERPLFIATRRLPAKVAAAAPITAKSDLPAAQFKLIGVLVSGGTRQ…
A0A1F6RHN6 143-268 None
A0A3D6A667 1-185 None
C6XET1 5-148 None
A0L661 1-192 None
A0A1Z9QQ43 20-171 None
A0A7Y2JJL1 361-497 None
A0A4Q2XML1 28-203 None
A0A7X1B035 2-155 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.