DPCstruct | MC28075

Metacluster Properties and Pfam Annotations

Number of structural domains84
Mean domain length (aa)174 ± 30 aa
Standard deviation of domain lengths29.77
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score82.30
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)29.43
Pfam Score100.00
Assigned Pfam label(s) CL0023

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0D9WHI3 338-515 TLRTKTSIHEALSRKIQPVLALNKIDRFFLEQHVDGIQVYPKEGTVVFLSCLHGWAFSLSSFAKIYSSKYNVEESKMIDCGNFFDPA…
A0A0K0F4D9 281-450 FMNKMDRALLELQLGQEELFQTFQRIIENINVIIATYGDDDGPMGAIMVDPSVGNVGFGSGLHGWAFTLKQFAEIYAEKFGVQVEKL…
A0A443R2V6 475-678 None
A0A835LAA3 89-286 None
B9FKN5 582-715 None
A0A7J7IIU7 273-509 None
T1H201 1-157 None
A0A7R9B945 2-116 None
A0A1U7Y7E1 33-179 None
A0A2V2WQD0 3-145 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.