DPCstruct | MC28061

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)110 ± 9 aa
Standard deviation of domain lengths9.05
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score79.83
Mean fraction of residues predicted as intrinsically disordered0.39
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)34.87
Pfam Score100.00
Assigned Pfam label(s) PF17240

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E5XPL2 2-110 TKPARTKPNFFQWMAYAHGRKLPDSMQEWVKNDLTGDWAGPRHLWRSMVPFLPIFALILVLVPGQLWLRGAMVLLMVILALIFSGAY…
A0A2U1FF27 1-97 MIRPGVLRWIAYAFGARLPVRYAPWVLHDLTTRTWFLRHLARSAVQATPAALLALLPGPAWLRVALPLFVLVSTLFMATLFSPMVRE…
A0A1S1QJB3 27-141 None
I8QVB7 26-126 None
A0A178X5U9 109-218 None
A0A4Q7KFT8 1-106 None
A0A4R2JS93 2-112 None
A0A511D7U0 82-212 None
A0A358STS0 1-112 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.