DPCstruct | MC28059

Metacluster Properties and Pfam Annotations

Number of structural domains98
Mean domain length (aa)308 ± 80 aa
Standard deviation of domain lengths79.73
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score85.55
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)25.16
Pfam Score85.52
Assigned Pfam label(s) PF14960- PF02807- CL0286- CL0671- CL0068

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6P4YVF8 22-319 NNHMARCLTKEIYAKLRDKVTPSGYTLDKVIQTGVDNPGHPFIMTVGCVAGDEESYDVFAELLDPVIDDRHGGYAKDAVHKTDLNFE…
A0A811Z5C2 6-261 AAGDEESYDVCKELFDPILEDRPGGDEHKTGLNPDNLSRVRTGRSIRGFCLPPHCGRGERRALGKLAVEAPSSLAGDPAEQQQLIDD…
T1GFR8 1-238 None
A0A671U9K2 2-170 None
A0A0G4HNI4 2-267 None
A0A086KW13 383-789 None
A0A1Q9C880 14-262 None
A0A2G8LKB0 48-416 None
A0A6P8HWY1 2-309 None
A0A7S4PGS4 52-401 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.