DPCstruct | MC28019

Metacluster Properties and Pfam Annotations

Number of structural domains40
Mean domain length (aa)124 ± 32 aa
Standard deviation of domain lengths32.15
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score71.04
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)31.72
Pfam Score98.21
Assigned Pfam label(s) PF05910- PF01699

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A822ZGJ0 24-105 CKNLSLNGLCISVQGPEGDNQCNCKAELKPWYFWRKQGSKRFIEEDKAVDVFWDLKAASLNGETEPHSDYYVAVISEDEVVL
A0A5D2C075 3-125 SPTLLVPSLQNQVSAIYKVILSTKKPLLVRVTWCKNQTGQGLILNFGDDDEDDPSTCFKLNTNLRFFRKKKGNKVIEANHSKIEVFW…
A0A843XC87 1-134 None
A0A7I8I860 2-83 None
A0A6A6N8L5 2-153 None
A0A835N2T5 8-157 None
A0A4S4CZH3 623-750 None
U5DBW6 1-132 None
A9P7T8 1-207 None
A0A067JJI9 480-564 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.