DPCstruct | MC28009

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)118 ± 12 aa
Standard deviation of domain lengths11.68
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score88.46
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)34.14
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A345R6R5 147-267 EFNPTIPNCVSYVQPADFSIRHGNSARALCDLAGQKGYDLVAATDVNLIFVESALSDAVIGNDKPTLEQLRSEDKHVSYVFAGYNGE…
A0A838HDP9 1-131 MEFNPTASNELYFVQDPDPALNQGSSLLAFVDLAKSKGYELVATTTTNAFFVVAEEYVQFRIDDNSIDAMHEVYMDMQICQGYDGSI…
A0A259M9D4 407-523 None
A7BRZ7 157-279 None
Q3ASK6 70-183 None
A0A0F9A491 3-101 None
A0A521QQ93 472-596 None
A0A7S4MYP3 15-116 None
R9J638 296-394 None
A0A7W8MYM8 93-219 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.