DPCstruct | MC28008

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)160 ± 47 aa
Standard deviation of domain lengths47.12
Length coefficient of variation0.29
Mean AlphaFold2 pLDDT confidence score85.56
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)25.89
Pfam Score90.00
Assigned Pfam label(s) CL0248- CL0263

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7X2N0Y3 14-113 INSTGEKLTAADLIRNYIMMRRTNDEQETIYKKYWLKLEKIFPESKKLAEFIRFYLATKMYTLTTEKDLYQVFKDYWKALDGENKYL…
A0A838HCR9 13-235 LPHQDSRMTQAHQFFSEAMTNWLTTGNSESRAETLTQVLLNGLQLVVIQLEADEDSQEIFETLNARGTPLTAADLIKNFVFQRLDLP…
A0A1T4ZHJ8 195-332 None
A0A1C6C4E7 203-332 None
A0A1I3YWB2 21-225 None
A0A844FJC7 1-120 None
A0A7Y0IQ99 139-283 None
A0A1M5HZN0 18-240 None
A0A1I7IAC3 202-324 None
W1F8Q1 18-162 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.