DPCstruct | MC28003

Metacluster Properties and Pfam Annotations

Number of structural domains63
Mean domain length (aa)143 ± 23 aa
Standard deviation of domain lengths23.18
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score80.32
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)20.29
Pfam Score97.92
Assigned Pfam label(s) CL0482- PF05697

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H5XS31 2-142 NFEIKNISSTIFEISGSFKEEEIKEVYQRELERLAKSVKIPGFRPGKVPIEIIERKYGEEAKNNAVRSKIADIIEQETKKKDKWIEV…
A0A7V2CZ81 23-154 NVEVESLPNCVTSLRVEVPPDRVEGEWARVAADFRAHARVPGFRPGKVPAAVIEKRFEKEIREELTRKLLSETTREVIRERKLRVLS…
A0A2E2WUR6 2-129 None
T2RDT5 3-148 None
A0A2T2UG74 5-155 None
A0A7W0PYN9 1-155 None
A0A1W9P507 24-180 None
W2UZT8 60-221 None
A0A1A9VKD8 19-172 None
A0A535PDF1 7-110 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.