DPCstruct | MC27991

Metacluster Properties and Pfam Annotations

Number of structural domains27
Mean domain length (aa)102 ± 17 aa
Standard deviation of domain lengths16.96
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score63.66
Mean fraction of residues predicted as intrinsically disordered0.68
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)46.52
Pfam Score100.00
Assigned Pfam label(s) CL0114

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A452XAX7 3-90 CTDCRRNQPLPPLASPTSSDASPRAPFVVKPPEKKHRLPSAYNRFMREEIQRIKAAKPDIPHREAFSMAAKNWAKCDPRCSSTVSASN
A0A426XDU7 19-118 PRDVIQCLCPAGPQMGFQGPCTGLMMEPPSLRSSSSGEQFKKASLITVPKKHRAPSAYNHFMREEIQRIKAAKPDIPHREAFSMAAK…
A0A067GY42 5-122 None
A0A0H2RHI8 1-91 None
A2YMU8 28-128 None
A0A2Z6LZL1 18-126 None
A0A1R3I6W4 37-166 None
V4KXK1 79-156 None
A0A059C530 116-244 None
A0A061EB61 147-237 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.