DPCstruct | MC27977

Metacluster Properties and Pfam Annotations

Number of structural domains118
Mean domain length (aa)182 ± 39 aa
Standard deviation of domain lengths39.37
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score79.33
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)26.19
Pfam Score97.04
Assigned Pfam label(s) CL0020- CL0196- CL0109

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A067HDW3 4-185 ECWGDEVSKKVLWQYKSLPKKGKPQGREVTVLAAFLISSPSKDLEVVALGTGTKCIGRSLLSPHGDIVNDSHAEIVARRALLRFFYT…
A0A0D3K942 8-131 TDAAAIRLAVLDAYAALPATGKPQAGEWSVLAGIALRSASDALEVVALGTGTKCLTAKAIAAERSGGCLHDGHAEVCARRAFLRYLL…
A0A287X9M0 7-152 None
A0A1S3MQ20 491-607 None
A0A1S8W9D2 1-222 None
A0A6P6BWM4 41-201 None
A0A820HF06 1-166 None
G0PFK5 31-201 None
A0A7R9LBK9 7-181 None
A0A4Z2HFH5 26-227 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.