DPCstruct | MC27963

Metacluster Properties and Pfam Annotations

Number of structural domains79
Mean domain length (aa)127 ± 20 aa
Standard deviation of domain lengths19.86
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score86.16
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)28.06
Pfam Score93.28
Assigned Pfam label(s) CL0487- PF04189- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6I9PNW9 9-133 CIQDGDVAIVYLGHESMTPVKVKRGAQTQTRYGVIRHSTDLIGQRYGSKVTCSKGGWVYVLHPTPELWTVNLPHRTQILYTTDIATI…
A0A4W5QEK1 1-112 ASFIYSEFIQEGDVAIIILGHDSVMPVKVQQCSKTQTRHGVICHSKDLIGQRFGIMVTCSKGGWVYVLHPTNELWTLNLPHRTQILY…
A0A3Q0IVY2 3-108 None
A0A445CI45 10-118 None
A0A151BIP8 2-126 None
A0A6A2XB60 1-125 None
A0A0G4NMQ8 11-122 None
A0A5J5X482 7-102 None
A0A6A5QDA3 64-165 None
F2DU43 26-161 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.