DPCstruct | MC27908

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)345 ± 53 aa
Standard deviation of domain lengths52.79
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score75.02
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)32.45
Pfam Score100.00
Assigned Pfam label(s) PF04780

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
I1I738 60-423 EFVRGLDAAIDKRACLHRPLGFADRAAQSFPNSAVIAAFRARLLFVLGEHDAAERECRRAIALENPRDPGDDCVPPGSISAPDVNAR…
A0A0D3HLK5 2-342 DTAARTFDRSLVVALFRAKLLACLHDYDAAEAECRRALAVDNPDDPAAHEIPLGSAIGEEYDDMVSSLRKQLCDLQKKLVLLAVHDW…
A0A3L6SWL7 11-335 None
A0A0P0Y416 224-586 None
A0A1D6PR62 76-441 None
A0A0D9XCH4 186-614 None
A0A1Z5RJ69 180-584 None
A0A287QMQ7 31-344 None
A0A835ARE4 157-543 None
A0A0E0J3K4 73-437 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.