DPCstruct | MC27878

Metacluster Properties and Pfam Annotations

Number of structural domains776
Mean domain length (aa)264 ± 55 aa
Standard deviation of domain lengths55.36
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score84.09
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)16.13
Pfam Score98.23
Assigned Pfam label(s) CL0041- PF04574- CL0063- CL0110- CL0093

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2L0E3Y4 3-225 DFKMARRWLDSADAILISASNGLSITEGYNIFAYDQAFKDHFQQFHNQYGFMNILQGLTYQFPTPEERQVFYSAIFDYMVNNYQVSP…
T0L6G6 9-290 IQSNIHKFINKNVVIITGAGISVKAGIPDFRSKTGIFSDIYKKFKIKGEDLFTYKFGLNDSTRHIYINYIYNLKKLIDNAKPTFTHN…
A0A1Y2HEW2 6-261 None
A0A820BKE0 7-247 None
A0A820BUS7 270-478 None
A0A1Q7CNF1 3-200 None
B0EBU9 14-268 None
Q0YQN8 10-351 None
A0A653WM81 3-201 None
G9PL31 4-290 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.