DPCstruct | MC27841

Metacluster Properties and Pfam Annotations

Number of structural domains85
Mean domain length (aa)127 ± 23 aa
Standard deviation of domain lengths22.76
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score80.89
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)36.39
Pfam Score99.39
Assigned Pfam label(s) CL0346- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
T1EH42 2-97 LTAFFDTKENWEETSIVVGRPWKKDELRLKSNSDLHKLWYVLLKERNMLMTMEAEYNRQCELFPSPERLEKVEESMENILDVVRERN…
A0A2R5GKS1 6-128 RAAGALAGRRPTVGARPAAVTRGIEEFFDVRGEKSTDGTVETGRAWTADELRLKSFDDLRKLWFILLKEKNMLLTEKHLARSMGQPM…
T1PAG3 2-89 None
A0A6L5CLE2 16-98 None
A0A177B4N4 16-125 None
M1VHF1 36-176 None
F4Q5W8 18-152 None
A0A835JFB5 223-383 None
A0A7S4PGW4 1-112 None
A4RHR8 97-243 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.