DPCstruct | MC27838

Metacluster Properties and Pfam Annotations

Number of structural domains399
Mean domain length (aa)194 ± 27 aa
Standard deviation of domain lengths27.40
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score82.31
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)18.65
Pfam Score90.61
Assigned Pfam label(s) PF04526- CL0559- CL0328- CL0219- CL0188

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S3YPW2 3-149 SWGIVIPIGAMVARYLRQYDPIWFYSHTTIQSLGFLLGFAGIICGFILEDRLSVDVDRHKALGIFILVLGCLQVIAFLARPGKESKM…
A0A2R5GB27 456-637 FGSWMISAPKQLGIHGILMVLAWIFLIPGGTVPPLLFKHKEGNKWFLAHKSMMGLGIVFTLVAFFLIVPYKWGDNFGTTHGKIGLTI…
A0A803Q3H1 2-145 None
A0A226EV45 625-846 None
A0A530H5B4 3-202 None
A0A0G4HMB7 174-362 None
A0A1Y2H7Z4 22-219 None
A0A1J7IB61 2-180 None
A0A6A6KWW9 62-196 None
A0A066VVS5 2-203 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.