DPCstruct | MC27834

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)136 ± 9 aa
Standard deviation of domain lengths8.74
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score92.43
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)35.86
Pfam Score100.00
Assigned Pfam label(s) CL0733

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2C6IC06 137-271 RRPKDLLRGRNANGELEFGHWVNSVFRPYDDRAAIDGGSLEGKGLELAWLKSPLDLFLLQTQGSGRLRLQDGGEMFVGYDGRNGQPY…
M3IAW0 1-131 METPSDLIVKKDGNKKSVGKIINEVFVPYETREELSHTSVWKKRSKAIVYVKIVDLHLAQLEGSALVKVPDHIPFRITYSEDNGKEY…
A0A3E0NMD3 350-490 None
A0A6S7CLX0 50-192 None
A0A379GB30 1-145 None
A0A2T4JJ96 93-205 None
A0A7R9RB40 142-271 None
A0A7C5DR99 6-147 None
A0A1M7ZJC8 166-307 None
A0A812QW33 327-464 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.