DPCstruct | MC27821

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)117 ± 16 aa
Standard deviation of domain lengths15.59
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score72.91
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)34.23
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1X2HEI3 522-607 LPLKAHSLFELFADPNSDTPFIVNGPDGYAITSIEEARAHQDIMMGAFFDHDLIQSLCQKHGLSFRNRIRIGADGMALIEGRRSSP
A0A2G4T050 2-116 ASFSTMRVDAPSLFSLLNHAKSNNLLPLRDSDNFVIGSQDQARHHKDSVFTSIFDLEAVFSICKQPGLAFAQNITSLPGAKSVEMLG…
A0A197JD83 157-267 None
S2JQV1 88-218 None
A0A367KUN7 163-265 None
A0A1X0RXW6 428-564 None
A0A0B7N0S8 53-182 None
A0A0B7MWV9 99-205 None
A0A162THD6 265-366 None
A0A0B7MVS2 1-143 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.