DPCstruct | MC2777

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)76 ± 7 aa
Standard deviation of domain lengths6.66
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score81.01
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)34.12
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1M6JY28 20-93 MEIVCPVCNGLTPVEAFCPQCGEPMLDGGPVEDYLGSYSPYMEKGTCQEQNYCIHLLYCPDCHYDVRAAWEMII
A0A2A6DY77 2-83 RASICSVCNGLRPLHAVCPACGAEAVDSGRADEYWGPYAPYLPIDDLKMTNGLPDLARRECAHLARCPRCGTVSTVFVRERA
A0A3G1KN39 1-79 None
A0A2N0QL37 110-189 None
A0A1M5SRB6 33-108 None
A0A6N7ISA9 2-69 None
A0A7X7AFL1 10-72 None
A0A516KE69 3-72 None
A0A1X7FGR6 1-71 None
A0A1H5ZQG7 15-97 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.